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gaji kekurangan Penyimpangan insulin folding Mewakili pengiriman Elemental

Diabetes mellitus due to the toxic misfolding of proinsulin variants -  ScienceDirect
Diabetes mellitus due to the toxic misfolding of proinsulin variants - ScienceDirect

The A-chain of Insulin Contacts the Insert Domain of the Insulin Receptor -  ScienceDirect
The A-chain of Insulin Contacts the Insert Domain of the Insulin Receptor - ScienceDirect

Integrating insulin secretion and ER stress in pancreatic β-cells | Nature  Cell Biology
Integrating insulin secretion and ER stress in pancreatic β-cells | Nature Cell Biology

SOLVED:Folding : studies of insulin show that the mature proteins cannot be  refolded in manner similar to that Anfisen experiment: If mature insulin is  unfolded in urea and reduced and then refolded
SOLVED:Folding : studies of insulin show that the mature proteins cannot be refolded in manner similar to that Anfisen experiment: If mature insulin is unfolded in urea and reduced and then refolded

Proinsulin - Wikipedia
Proinsulin - Wikipedia

PLOS ONE: Human αB-crystallin as fusion protein and molecular chaperone  increases the expression and folding efficiency of recombinant insulin
PLOS ONE: Human αB-crystallin as fusion protein and molecular chaperone increases the expression and folding efficiency of recombinant insulin

Biosynthesis, structure, and folding of the insulin precursor protein - Liu  - 2018 - Diabetes, Obesity and Metabolism - Wiley Online Library
Biosynthesis, structure, and folding of the insulin precursor protein - Liu - 2018 - Diabetes, Obesity and Metabolism - Wiley Online Library

Facile folding of insulin variants bearing a prosthetic C-peptide prepared  by α-ketoacid-hydroxylamine (KAHA) ligation - Chemical Science (RSC  Publishing)
Facile folding of insulin variants bearing a prosthetic C-peptide prepared by α-ketoacid-hydroxylamine (KAHA) ligation - Chemical Science (RSC Publishing)

Design and Folding of [GluA4(OβThrB30)]Insulin (“Ester Insulin”): A Minimal  Proinsulin Surrogate that Can Be Chemically Converted into Human Insulin -  Sohma - 2010 - Angewandte Chemie International Edition - Wiley Online  Library
Design and Folding of [GluA4(OβThrB30)]Insulin (“Ester Insulin”): A Minimal Proinsulin Surrogate that Can Be Chemically Converted into Human Insulin - Sohma - 2010 - Angewandte Chemie International Edition - Wiley Online Library

The making of insulin in health and disease | SpringerLink
The making of insulin in health and disease | SpringerLink

The Folding Nucleus of the Insulin Superfamily - Journal of Biological  Chemistry
The Folding Nucleus of the Insulin Superfamily - Journal of Biological Chemistry

PLOS ONE: Human αB-crystallin as fusion protein and molecular chaperone  increases the expression and folding efficiency of recombinant insulin
PLOS ONE: Human αB-crystallin as fusion protein and molecular chaperone increases the expression and folding efficiency of recombinant insulin

Synthetic route to insulin-like peptides. i Synthesis of folded... |  Download Scientific Diagram
Synthetic route to insulin-like peptides. i Synthesis of folded... | Download Scientific Diagram

PDB-101: Molecule of the Month: Insulin
PDB-101: Molecule of the Month: Insulin

The making of insulin in health and disease | SpringerLink
The making of insulin in health and disease | SpringerLink

PDB-101: Global Health: Diabetes Mellitus: Drugs: Insulin: Insulin
PDB-101: Global Health: Diabetes Mellitus: Drugs: Insulin: Insulin

Insulin gene mutations as a cause of permanent neonatal diabetes | PNAS
Insulin gene mutations as a cause of permanent neonatal diabetes | PNAS

Type 2 Diabetes Mellitus as a Conformational Disease | Insight Medical  Publishing
Type 2 Diabetes Mellitus as a Conformational Disease | Insight Medical Publishing

Insulin Folding - see how it's done | Digital World Biology
Insulin Folding - see how it's done | Digital World Biology

Crystal Structure of a “Nonfoldable” Insulin - Journal of Biological  Chemistry
Crystal Structure of a “Nonfoldable” Insulin - Journal of Biological Chemistry

Insulin mRNA to Protein Kit© - Protein-Folding Kit
Insulin mRNA to Protein Kit© - Protein-Folding Kit

Contribution of Residue B5 to the Folding and Function of Insulin and IGF-I  - Journal of Biological Chemistry
Contribution of Residue B5 to the Folding and Function of Insulin and IGF-I - Journal of Biological Chemistry

Insulin Biosynthesis, Secretion, Structure, and Structure-Activity  Relationships - Endotext - NCBI Bookshelf
Insulin Biosynthesis, Secretion, Structure, and Structure-Activity Relationships - Endotext - NCBI Bookshelf

Facile folding of insulin variants bearing a prosthetic C-peptide prepared  by α-ketoacid-hydroxylamine (KAHA) ligation - Chemical Science (RSC  Publishing) DOI:10.1039/C8SC03738H
Facile folding of insulin variants bearing a prosthetic C-peptide prepared by α-ketoacid-hydroxylamine (KAHA) ligation - Chemical Science (RSC Publishing) DOI:10.1039/C8SC03738H

Insulin Biosynthesis, Secretion, Structure, and Structure-Activity  Relationships - Endotext - NCBI Bookshelf
Insulin Biosynthesis, Secretion, Structure, and Structure-Activity Relationships - Endotext - NCBI Bookshelf

Biosynthetic pathway of proinsulin. Insulin biosynthesis in -cells... |  Download Scientific Diagram
Biosynthetic pathway of proinsulin. Insulin biosynthesis in -cells... | Download Scientific Diagram